Molecular Profiling Reclassifies Adult Astroblastoma into Known and Clinically Distinct Tumor Entities with Frequent Mitogen‐Activated Protein Kinase Pathway Alterations

BACKGROUND. Astroblastoma (ABM) is a rare glial brain tumor. Recurrent meningioma 1 (MN1) alterations have been recently identified in most pediatric cases. Adolescent and adult cases, however, remain molecularly poorly defined. MATERIALS AND METHODS. We performed clinical and molecular characteriza...

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Vydáno v:Oncologist
Hlavní autoři: Boisseau, William, Euskirchen, Philipp, Mokhtari, Karima, Dehais, Caroline, Touat, Mehdi, Hoang‐Xuan, Khê, Sanson, Marc, Capelle, Laurent, Nouet, Aurélien, Karachi, Carine, Bielle, Franck, Guégan, Justine, Marie, Yannick, Martin‐Duverneuil, Nadine, Taillandier, Luc, Rousseau, Audrey, Delattre, Jean‐Yves, Idbaih, Ahmed
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Inc. 2019
Témata:
Neuro‐Oncology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6975955/
https://ncbi.nlm.nih.gov/pubmed/31346129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2019-0223
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