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Comprehensive molecular characterization of inhibitors of apoptosis proteins (IAPs) for therapeutic targeting in cancer

BACKGROUND: Inhibitors of apoptosis proteins (IAPs) are a family of antiapoptotic proteins modulating cell cycle, signal transduction and apoptosis. Dysregulated IAPs have been reported to contribute to tumor progression and chemoresistance in various cancers. However, existing studies were sporadic...

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Podrobná bibliografie
Vydáno v:BMC Med Genomics
Hlavní autoři: Liang, Jianfeng, Zhao, Wanni, Tong, Pan, Li, Ping, Zhao, Yuanli, Li, Hua, Liang, Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6975060/
https://ncbi.nlm.nih.gov/pubmed/31964418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-020-0661-x
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