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4-AP-3-MeOH Promotes Structural and Functional Spontaneous Recovery in the Acute Sciatic Nerve Stretch Injury

BACKGROUND: 4-AP-3-MeOH, a derivative of 4-aminopyridine, was developed and demonstrated to prevent nerve pulse diffusion due to myelin damage and significantly enhance axonal conduction following nerve injury. Currently, repurposing the existing drug such as 4-AP-3-MeOH to restore motor function is...

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Detalhes bibliográficos
Publicado no:Dose Response
Main Authors: Chen, Yan, Wang, Weidong, Zhao, Zhimin, Ren, Dong, Xin, Danmou
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6974761/
https://ncbi.nlm.nih.gov/pubmed/32009855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1559325819899254
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