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Proteostasis failure and cellular senescence in long‐term cultured postmitotic rat neurons
Cellular senescence, a stress‐induced irreversible cell cycle arrest, has been defined for mitotic cells and is implicated in aging of replicative tissues. Age‐related functional decline in the brain is often attributed to a failure of protein homeostasis (proteostasis), largely in postmitotic neuro...
Sparad:
| I publikationen: | Aging Cell |
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| Huvudupphovsmän: | , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
John Wiley and Sons Inc.
2019
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6974705/ https://ncbi.nlm.nih.gov/pubmed/31762159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13071 |
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