Using Precisely Defined in vivo Microbiotas to Understand Microbial Regulation of IgE

Early life exposure to microbes plays an important role in immune system development. Germ-free mice, or mice colonized with a low-diversity microbiota, exhibit high serum IgE levels. An increase in microbial richness, providing it occurs in a critical developmental window early in life, leads to in...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Wyss, Madeleine, Brown, Kirsty, Thomson, Carolyn A., Koegler, Mia, Terra, Fernanda, Fan, Vina, Ronchi, Francesca, Bihan, Dominique, Lewis, Ian, Geuking, Markus B., McCoy, Kathy D.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6974480/
https://ncbi.nlm.nih.gov/pubmed/32010146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.03107
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