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Inhibition of Amyloid-Beta Production, Associated Neuroinflammation, and Histone Deacetylase 2-Mediated Epigenetic Modifications Prevent Neuropathology in Alzheimer’s Disease in vitro Model

Alzheimer’s disease (AD) is a growing global threat to healthcare in the aging population. In the USA alone, it is estimated that one in nine persons over the age of 65 years is living with AD. The pathology is marked by the accumulation of amyloid-beta (Aβ) deposition in the brain, which is further...

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Библиографические подробности
Опубликовано в: :Front Aging Neurosci
Главные авторы: Atluri, Venkata Subba Rao, Tiwari, Sneham, Rodriguez, Melisa, Kaushik, Ajeet, Yndart, Adriana, Kolishetti, Nagesh, Yatham, Mohan, Nair, Madhavan
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6974446/
https://ncbi.nlm.nih.gov/pubmed/32009938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2019.00342
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