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Inhibition of Amyloid-Beta Production, Associated Neuroinflammation, and Histone Deacetylase 2-Mediated Epigenetic Modifications Prevent Neuropathology in Alzheimer’s Disease in vitro Model

Alzheimer’s disease (AD) is a growing global threat to healthcare in the aging population. In the USA alone, it is estimated that one in nine persons over the age of 65 years is living with AD. The pathology is marked by the accumulation of amyloid-beta (Aβ) deposition in the brain, which is further...

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Dettagli Bibliografici
Pubblicato in:Front Aging Neurosci
Autori principali: Atluri, Venkata Subba Rao, Tiwari, Sneham, Rodriguez, Melisa, Kaushik, Ajeet, Yndart, Adriana, Kolishetti, Nagesh, Yatham, Mohan, Nair, Madhavan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6974446/
https://ncbi.nlm.nih.gov/pubmed/32009938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2019.00342
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