Relaxation of synaptic inhibitory events as a compensatory mechanism in fetal SOD spinal motor networks

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease affecting motor neurons (MNs) during late adulthood. Here, with the aim of identifying early changes underpinning ALS neurodegeneration, we analyzed the GABAergic/glycinergic inputs to E17.5 fetal MNs from SOD1(G93A) (SOD...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Branchereau, Pascal, Martin, Elodie, Allain, Anne-Emilie, Cazenave, William, Supiot, Laura, Hodeib, Fara, Laupénie, Amandine, Dalvi, Urvashi, Zhu, Hongmei, Cattaert, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6974356/
https://ncbi.nlm.nih.gov/pubmed/31868588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.51402
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