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The Impact of Loading Dose on Outcome in Stroke Patients Receiving Low-Dose Tissue Plasminogen Activator Thrombolytic Therapy

BACKGROUND: Intravenous tissue plasminogen activator (tPA) (0.9 mg/kg, maximum 90 mg) with a bolus of 10% of the total dose given within 1–2 mins is the standard therapy for patients receiving thrombolytic therapy. Low-dose (0.6 mg/kg) tPA is also approved for thrombolytic therapy for ischemic strok...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Wong, Yi-Sin, Sung, Sheng-Feng, Wu, Chi-Shun, Hsu, Yung-Chu, Su, Yu-Hsiang, Hung, Ling-Chien, Ong, Cheung-Ter
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6974114/
https://ncbi.nlm.nih.gov/pubmed/32021109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S235388
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