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Meta‐analysis and Mendelian randomization: A review

Mendelian randomization (MR) uses genetic variants as instrumental variables to infer whether a risk factor causally affects a health outcome. Meta‐analysis has been used historically in MR to combine results from separate epidemiological studies, with each study using a small but select group of ge...

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Bibliografische gegevens
Gepubliceerd in:Res Synth Methods
Hoofdauteurs: Bowden, Jack, Holmes, Michael V.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6973275/
https://ncbi.nlm.nih.gov/pubmed/30861319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jrsm.1346
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