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Fast and fierce versus slow and smooth: Heterogeneity in immune responses to Plasmodium in the controlled human malaria infection model

Controlled human malaria infection (CHMI) is an established model in clinical malaria research. Upon exposure to Plasmodium falciparum parasites, malaria‐naive volunteers differ in dynamics and composition of their immune profiles and subsequent capacity to generate protective immunity. CHMI volunte...

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Bibliographische Detailangaben
Veröffentlicht in:Immunol Rev
Hauptverfasser: Yap, Xi Zen, McCall, Matthew B. B., Sauerwein, Robert W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6973142/
https://ncbi.nlm.nih.gov/pubmed/31605396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12811
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