Quinoline‐Conjugated Ruthenacarboranes: Toward Hybrid Drugs with a Dual Mode of Action

The role of autophagy in cancer is often complex, ranging from tumor‐promoting to ‐suppressing effects. In this study, two novel hybrid molecules were designed, containing a ruthenacarborane fragment conjugated with a known modulator of autophagy, namely a quinoline derivative. The complex closo‐[3‐...

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Publicat a:ChemMedChem
Autors principals: Gozzi, Marta, Murganic, Blagoje, Drača, Dijana, Popp, John, Coburger, Peter, Maksimović‐Ivanić, Danijela, Mijatović, Sanja, Hey‐Hawkins, Evamarie
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6973020/
https://ncbi.nlm.nih.gov/pubmed/31675152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201900349
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