Activated M2 Macrophages Contribute to the Pathogenesis of IgG4‐Related Disease via Toll‐like Receptor 7/Interleukin‐33 Signaling

OBJECTIVE: IgG4‐related disease (IgG4‐RD) is a unique inflammatory disorder in which Th2 cytokines promote IgG4 production. In addition, recent studies have implicated the Toll‐like receptor (TLR) pathway. This study was undertaken to examine the expression of TLRs in salivary glands (SGs) from pati...

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Publicado en:Arthritis Rheumatol
Autores principales: Ishiguro, Noriko, Moriyama, Masafumi, Furusho, Katsuhiro, Furukawa, Sachiko, Shibata, Takuma, Murakami, Yusuke, Chinju, Akira, Haque, A. S. M. Rafiul, Gion, Yuka, Ohta, Miho, Maehara, Takashi, Tanaka, Akihiko, Yamauchi, Masaki, Sakamoto, Mizuki, Mochizuki, Keita, Ono, Yuko, Hayashida, Jun‐Nosuke, Sato, Yasuharu, Kiyoshima, Tamotsu, Yamamoto, Hidetaka, Miyake, Kensuke, Nakamura, Seiji
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2019
Materias:
IgG4‐Related Disease
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6972995/
https://ncbi.nlm.nih.gov/pubmed/31339007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.41052
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