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Pharmacological enrichment of polygenic risk for precision medicine in complex disorders
Individuals with complex disorders typically have a heritable burden of common variation that can be expressed as a polygenic risk score (PRS). While PRS has some predictive utility, it lacks the molecular specificity to be directly informative for clinical interventions. We therefore sought to deve...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6972917/ https://ncbi.nlm.nih.gov/pubmed/31964963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57795-0 |
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