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Long-term Proton Pump Inhibitor Administration Caused Physiological and Microbiota Changes in Rats

Proton pump inhibitors (PPIs) are used for the long-term treatment of gastroesophageal disorders and the non-prescription medicines for acid reflux. However, there is growing concerns about PPI misuse, overuse and abuse. This study aimed to develop an animal model to examine the effects of long-term...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yang, Yu-Chen S. H., Chang, Hsuen-Wen, Lin, I-Hsuan, Chien, Li-Nien, Wu, Min-Ju, Liu, Yun-Ru, Chu, Peiguo G., Xie, Guoxiang, Dong, Fangcong, Jia, Wei, Chang, Vincent H. S., Yen, Yun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6972906/
https://ncbi.nlm.nih.gov/pubmed/31964941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57612-8
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