IL‐32 and its splice variants are associated with protection against Mycobacterium tuberculosis infection and skewing of Th1/Th17 cytokines

Studies in IL‐32 transgenic mice and in vitro suggest that IL‐32 may have protective effects against Mycobacterium tuberculosis, but so far there are barely any studies in humans. We studied the role of IL‐32 and its splice variants in tuberculosis (TB) in vivo and in vitro. Blood transcriptional an...

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Detalhes bibliográficos
Publicado no:J Leukoc Biol
Main Authors: Koeken, Valerie A. C. M., Verrall, Ayesha J., Ardiansyah, Edwin, Apriani, Lika, dos Santos, Jéssica C., Kumar, Vinod, Alisjahbana, Bachti, Hill, Philip C., Joosten, Leo A. B., van Crevel, Reinout, van Laarhoven, Arjan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Host Defense & Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6972663/
https://ncbi.nlm.nih.gov/pubmed/31378983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.4AB0219-071R
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