Effects of Maribavir on P‐Glycoprotein and CYP2D6 in Healthy Volunteers

Maribavir is an investigational drug being evaluated in transplant recipients with cytomegalovirus infection. To understand potential drug‐drug interactions, we examined the effects of multiple doses of maribavir on cytochrome P450 (CYP) 2D6 and P‐glycoprotein (P‐gp) activity using probe substrates...

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Detalhes bibliográficos
Publicado no:J Clin Pharmacol
Main Authors: Song, Ivy H., Ilic, Katarina, Murphy, Joseph, Lasseter, Kenneth, Martin, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Drug Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6972521/
https://ncbi.nlm.nih.gov/pubmed/31385617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.1504
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