TSPO Ligands Boost Mitochondrial Function and Pregnenolone Synthesis

 Translocator protein 18 kDa (TSPO) is located in the mitochondrial outer membrane and plays an important role in steroidogenesis and cell survival. In the central nervous system (CNS), its expression is upregulated in neuropathologies such as Alzheimer’s disease (AD). Previously, we demonstrated th...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Lejri, Imane, Grimm, Amandine, Hallé, François, Abarghaz, Mustapha, Klein, Christian, Maitre, Michel, Schmitt, Martine, Bourguignon, Jean-Jacques, Mensah-Nyagan, Ayikoe Guy, Bihel, Frederic, Eckert, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6971832/
https://ncbi.nlm.nih.gov/pubmed/31256132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-190127
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