Abnormalities of DYRK1A-Cytoskeleton Complexes in the Blood Cells as Potential Biomarkers of Alzheimer’s Disease

BACKGROUND: DYRK1A is implicated in mental retardation and Alzheimer’s disease (AD) dementia of Down syndrome (DS) individuals. The protein is associated with cytoskeleton and altered expression has been shown to impair the cytoskeletal network via dosage effect. OBJECTIVE: Our original observations...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Alzheimers Dis
मुख्य लेखकों: Dowjat, Karol, Adayev, Tatyana, Wojda, Urszula, Brzozowska, Katarzyna, Barczak, Anna, Gabryelewicz, Tomasz, Hwang, Yu-Wen
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: IOS Press 2019
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6971831/
https://ncbi.nlm.nih.gov/pubmed/31683476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-190475
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