Life-extending dietary restriction, but not dietary supplementation of branched-chain amino acids, can increase organismal oxidation rates of individual branched-chain amino acids by grasshoppers

BACKGROUND: Life-extending dietary restriction increases energy demands. Branched-chain amino acids (BCAAs), at high levels, may be detrimental to healthspan by activating the mechanistic Target of Rapamycin (mTOR). Whether organismal oxidation of BCAAs increases upon dietary restriction is unknown....

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Vydáno v:Nutr Healthy Aging
Hlavní autoři: Hatle, J.D., Karjasevic, A., Rehfeldt, E., Nagle, F.S., Milano, L.J., Patel, S., Hiatt, D., McCue, M.D.
Médium: Artigo
Jazyk:Inglês
Vydáno: IOS Press 2019
Témata:
Research Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6971830/
https://ncbi.nlm.nih.gov/pubmed/31984246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/NHA-190073
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