Assessment of MTNR1B Type 2 Diabetes Genetic Risk Modification by Shift Work and Morningness-Eveningness Preference in the UK Biobank

Night shift work, behavioral rhythms, and the common MTNR1B risk single nucleotide polymorphism (SNP), rs10830963, associate with type 2 diabetes; however, whether they exert joint effects to exacerbate type 2 diabetes risk is unknown. Among employed participants of European ancestry in the UK Bioba...

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Veröffentlicht in:Diabetes
Hauptverfasser: Dashti, Hassan S., Vetter, Céline, Lane, Jacqueline M., Smith, Matt C., Wood, Andrew R., Weedon, Michael N., Rutter, Martin K., Garaulet, Marta, Scheer, Frank A.J.L., Saxena, Richa
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Diabetes Association 2020
Schlagworte:
Genetics/Genomes/Proteomics/Metabolomics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6971490/
https://ncbi.nlm.nih.gov/pubmed/31757795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db19-0606
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