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P53 and Parkin co-regulate mitophagy in bone marrow mesenchymal stem cells to promote the repair of early steroid-induced osteonecrosis of the femoral head

Survival and stemness of bone marrow mesenchymal stem cells (BMSCs) in osteonecrotic areas are especially important in the treatment of early steroid-induced osteonecrosis of the femoral head (ONFH). We had previously used BMSCs to repair early steroid-induced ONFH, but the transplanted BMSCs underw...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Zhang, Fei, Peng, Wuxun, Zhang, Jian, Dong, Wentao, Wu, Jianhua, Wang, Tao, Xie, Zhihong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6971291/
https://ncbi.nlm.nih.gov/pubmed/31959744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2238-1
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