Analysis of O-glycoforms of the IgA1 hinge region by sequential deglycosylation

A common renal disease, immunoglobulin A (IgA) nephropathy (IgAN), is associated with glomerular deposition of IgA1-containing immune complexes. IgA1 hinge region (HR) has up to six clustered O-glycans consisting of Ser/Thr-linked N-acetylgalactosamine with β1,3-linked galactose and variable sialyla...

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Pubblicato in:Sci Rep
Autori principali: Ohyama, Yukako, Yamaguchi, Hisateru, Nakajima, Kazuki, Mizuno, Tomohiro, Fukamachi, Yukihiro, Yokoi, Yasuto, Tsuboi, Naotake, Inaguma, Daijo, Hasegawa, Midori, Renfrow, Matthew B., Novak, Jan, Yuzawa, Yukio, Takahashi, Kazuo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6971281/
https://ncbi.nlm.nih.gov/pubmed/31959827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57510-z
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