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Improved multiparametric scrape loading-dye transfer assay for a simultaneous high-throughput analysis of gap junctional intercellular communication, cell density and viability

Gap junctional intercellular communication (GJIC) is a vital cellular process required for maintenance of tissue homeostasis. In vitro assessment of GJIC represents valuable phenotypic endpoint that could be effectively utilized as an integral component in modern toxicity testing, drug screening or...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Dydowiczová, Aneta, Brózman, Ondřej, Babica, Pavel, Sovadinová, Iva
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6971000/
https://ncbi.nlm.nih.gov/pubmed/31959888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57536-3
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