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Hair follicle stem cells regulate retinoid metabolism to maintain the self-renewal niche for melanocyte stem cells

Metabolites are major biological parameters sensed by many cell types in vivo, whether they function as signaling mediators of SC and niche cross talk to regulate tissue regeneration is largely unknown. We show here that deletion of the Notch pathway co-factor RBP-J specifically in mouse HFSCs trigg...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Lu, Zhiwei, Xie, Yuhua, Huang, Huanwei, Jiang, Kaiju, Zhou, Bin, Wang, Fengchao, Chen, Ting
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6970533/
https://ncbi.nlm.nih.gov/pubmed/31898934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.52712
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