YAP1 and TAZ negatively control bone angiogenesis by limiting hypoxia-inducible factor signaling in endothelial cells

Blood vessels are integrated into different organ environments with distinct properties and physiology (Augustin and Koh, 2017). A striking example of organ-specific specialization is the bone vasculature where certain molecular signals yield the opposite effect as in other tissues (Glomski et al.,...

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Vydáno v:eLife
Hlavní autoři: Sivaraj, Kishor K, Dharmalingam, Backialakshmi, Mohanakrishnan, Vishal, Jeong, Hyun-Woo, Kato, Katsuhiro, Schröder, Silke, Adams, Susanne, Koh, Gou Young, Adams, Ralf H
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2020
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6970532/
https://ncbi.nlm.nih.gov/pubmed/31958058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.50770
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