Depotentiation depends on IP(3) receptor activation sustained by synaptic inputs after LTP induction

In CA1 neurons of guinea pig hippocampal slices, long-term potentiation (LTP) was induced in field excitatory postsynaptic potentials (EPSPs) or population spikes (PSs) by the delivery of high-frequency stimulation (HFS, 100 pulses at 100 Hz) to CA1 synapses, and was reversed by the delivery of a tr...

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Publicado en:Learn Mem
Main Authors: Fujii, Satoshi, Yamazaki, Yoshihiko, Goto, Jun-ichi, Fujiwara, Hiroki, Mikoshiba, Katsuhiko
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2020
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6970427/
https://ncbi.nlm.nih.gov/pubmed/31949037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.050344.119
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