Minimal B Cell Extrinsic IgG Glycan Modifications of Pro- and Anti-Inflammatory IgG Preparations in vivo

Select residues in the biantennary sugar moiety attached to the fragment crystallizable of immunoglobulin G (IgG) antibodies can modulate IgG effector functions. Thus, afucosylated IgG glycovariants have enhanced cytotoxic activity, whereas IgG glycovariants rich in terminal sialic acid residues can...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Schaffert, Anja, Hanić, Maja, Novokmet, Mislav, Zaytseva, Olga, Krištić, Jasminka, Lux, Anja, Nitschke, Lars, Peipp, Matthias, Pezer, Marija, Hennig, René, Rapp, Erdmann, Lauc, Gordan, Nimmerjahn, Falk
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6970187/
https://ncbi.nlm.nih.gov/pubmed/31998308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.03024
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