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CCN1 stimulated the osteoblasts via PTEN/AKT/GSK3β/cyclinD1 signal pathway in Myeloma Bone Disease

BACKGROUNDS: Myeloma‐related bone disease (MBD) is a common complication of multiple myeloma (MM), which can both decrease life quality and influence the prognosis of the patients. We have found that CCN1 stimulated proliferation and differentiation of osteoblasts in MM in vitro and in vivo, while i...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Yan, Siyang, Liu, Hui, Liu, Zhaoyun, Peng, Fengping, Jiang, Fengjuan, Li, Lijuan, Fu, Rong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6970049/
https://ncbi.nlm.nih.gov/pubmed/31769620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2608
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