MUC1 as a target for CAR‐T therapy in head and neck squamous cell carinoma

The modification of chimeric antigen receptor (CAR) endowing T cells with tumor‐specific cytotoxicity induces antitumor immunity. However, the structural characteristics of solid tumors, the loss of specific antigens, and the strong immunosuppressive environment are challenges to treat solid tumors...

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Med
Hauptverfasser: Mei, Zi, Zhang, Kai, Lam, Alfred King‐Yin, Huang, Junwen, Qiu, Feng, Qiao, Bin, Zhang, Yi
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Clinical Cancer Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6970025/
https://ncbi.nlm.nih.gov/pubmed/31800160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2733
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