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Microglial depletion and repopulation in brain slice culture normalizes sensitized proinflammatory signaling

BACKGROUND: Microglia are critical mediators of neuroimmune pathology across multiple neurologic disorders. Microglia can be persistently activated or “primed” by Toll-like receptor (TLR) activation, ethanol, stress, and other insults. Thus, strategies to prevent or reverse microglial priming may be...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Coleman, Leon G., Zou, Jian, Crews, Fulton T.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6969463/
https://ncbi.nlm.nih.gov/pubmed/31954398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1678-y
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