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Development of elastin-like polypeptide for targeted specific gene delivery in vivo

BACKGROUND: The successful deliveries of siRNA depend on their stabilities under physiological conditions because greater in vivo stability enhances cellular uptake and enables endosomal escape. Viral-based systems appears as most efficient approaches for gene delivery but often compromised in terms...

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Publicado en:J Nanobiotechnology
Main Authors: Yi, Aena, Sim, Dahye, Lee, Young-Jin, Sarangthem, Vijaya, Park, Rang-Woon
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6969399/
https://ncbi.nlm.nih.gov/pubmed/31952530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-020-0574-z
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