Design and Molecular dynamic Investigations of 7,8-Dihydroxyflavone Derivatives as Potential Neuroprotective Agents Against Alpha-synuclein

Parkinson’s disease (PD) is the second most common neurodegenerative disorder caused due to loss of dopaminergic neurons in substantia nigra pars compacta, which occurs the presence of Lewy bodies made up of Alpha-synuclein (ASN) aggregation resulting in neuronal death. This study aims to identify p...

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Vydáno v:Sci Rep
Hlavní autoři: Thangavel, Mohankumar, Chandramohan, Vivek, Shankaraiah, Lalithamba Haralur, Jayaraj, Richard L., Poomani, Kumaradhas, Magudeeswaran, Sivanandam, Govindasamy, Hunday, Vijayakumar, Rajendran, Rangasamy, Balakrishnan, Dharmar, Manimaran, Namasivayam, Elangovan
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6969171/
https://ncbi.nlm.nih.gov/pubmed/31953434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57417-9
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