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Zebrafish C-reactive protein isoforms inhibit SVCV replication by blocking autophagy through interactions with cell membrane cholesterol

In the present work, the mechanisms involved in the recently reported antiviral activity of zebrafish C-reactive protein-like protein (CRP1-7) against the spring viraemia of carp rhabdovirus (SVCV) in fish are explored. The results neither indicate blocking of the attachment or the binding step of t...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bello-Perez, Melissa, Pereiro, Patricia, Coll, Julio, Novoa, Beatriz, Perez, Luis, Falco, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6969114/
https://ncbi.nlm.nih.gov/pubmed/31953490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57501-0
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