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Human antibodies neutralizing diphtheria toxin in vitro and in vivo

Diphtheria is an infectious disease caused by Corynebacterium diphtheriae. The bacterium primarily infects the throat and upper airways and the produced diphtheria toxin (DT), which binds to the elongation factor 2 and blocks protein synthesis, can spread through the bloodstream and affect organs, s...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Wenzel, Esther Veronika, Bosnak, Margarita, Tierney, Robert, Schubert, Maren, Brown, Jeffrey, Dübel, Stefan, Efstratiou, Androulla, Sesardic, Dorothea, Stickings, Paul, Hust, Michael
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6969050/
https://ncbi.nlm.nih.gov/pubmed/31953428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-57103-5
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