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CNP mediated selective toxicity on melanoma cells is accompanied by mitochondrial dysfunction

Cerium (Ce) oxide nanoparticles (CNP; nanoceria) are reported to have cytotoxic effects on certain cancerous cell lines, while at the same concentration they show no cytotoxicity on normal (healthy) cells. Redox-active CNP exhibit both selective prooxidative as well as antioxidative properties. The...

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Pubblicato in:PLoS One
Autori principali: Aplak, Elif, von Montfort, Claudia, Haasler, Lisa, Stucki, David, Steckel, Bodo, Reichert, Andreas S., Stahl, Wilhelm, Brenneisen, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6968876/
https://ncbi.nlm.nih.gov/pubmed/31951630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0227926
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