CHROMATIX: computing the functional landscape of many-body chromatin interactions in transcriptionally active loci from deconvolved single cells

Chromatin interactions are important for gene regulation and cellular specialization. Emerging evidence suggests many-body spatial interactions play important roles in condensing super-enhancer regions into a cohesive transcriptional apparatus. Chromosome conformation studies using Hi-C are limited...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genome Biol
Prif Awduron: Perez-Rathke, Alan, Sun, Qiu, Wang, Boshen, Boeva, Valentina, Shao, Zhifeng, Liang, Jie
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2020
Pynciau:
Method
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6966897/
https://ncbi.nlm.nih.gov/pubmed/31948478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-019-1904-z
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