Enhanced Hsa-miR-181d/p-STAT3 and Hsa-miR-181d/p-STAT5A Ratios Mediate the Anticancer Effect of Garcinol in STAT3/5A-Addicted Glioblastoma

Background: Glioblastoma (GBM), a malignant grade IV tumor, is the most malignant brain tumor due to its hyper-proliferative and apoptosis-evading characteristics. The signal transducer and activators of transcription (STAT) family genes, including STAT3 and STAT5A, have been indicated to play impor...

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Bibliographic Details
Published in:Cancers (Basel)
Main Authors: Liu, Heng-Wei, Lee, Peter Mingjui, Bamodu, Oluwaseun Adebayo, Su, Yu-Kai, Fong, Iat-Hang, Yeh, Chi-Tai, Chien, Ming-Hsien, Kan, I-Hung, Lin, Chien-Min
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6966688/
https://ncbi.nlm.nih.gov/pubmed/31783691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11121888
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