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Potent Antitumor Activity of Liposomal Irinotecan in an Organoid- and CRISPR-Cas9-Based Murine Model of Gallbladder Cancer

Gallbladder cancer is associated with a dismal prognosis, and accurate in vivo models will be elemental to improve our understanding of this deadly disease and develop better treatment options. We have generated a transplantation-based murine model for gallbladder cancer that histologically mimics t...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Principais autores: Erlangga, Zulrahman, Wolff, Katharina, Poth, Tanja, Peltzer, Alexander, Nahnsen, Sven, Spielberg, Steffi, Timrott, Kai, Woller, Norman, Kühnel, Florian, Manns, Michael P., Saborowski, Anna, Vogel, Arndt, Saborowski, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6966678/
https://ncbi.nlm.nih.gov/pubmed/31795490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11121904
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