The Benzimidazole-Based Anthelmintic Parbendazole: A Repurposed Drug Candidate That Synergizes with Gemcitabine in Pancreatic Cancer

Pancreatic cancer (PC) is one of the most lethal, chemoresistant malignancies and it is of paramount importance to find more effective therapeutic agents. Repurposing of non-anticancer drugs may expand the repertoire of effective molecules. Studies on repurposing of benzimidazole-based anthelmintics...

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Détails bibliographiques
Publié dans:Cancers (Basel)
Auteurs principaux: Florio, Rosalba, Veschi, Serena, di Giacomo, Viviana, Pagotto, Sara, Carradori, Simone, Verginelli, Fabio, Cirilli, Roberto, Casulli, Adriano, Grassadonia, Antonino, Tinari, Nicola, Cataldi, Amelia, Amoroso, Rosa, Cama, Alessandro, De Lellis, Laura
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6966614/
https://ncbi.nlm.nih.gov/pubmed/31861153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11122042
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