Autophagy-Dependent Reactivation of Epstein-Barr Virus Lytic Cycle and Combinatorial Effects of Autophagy-Dependent and Independent Lytic Inducers in Nasopharyngeal Carcinoma

Autophagy, a conserved cellular mechanism, is manipulated by a number of viruses for different purposes. We previously demonstrated that an iron-chelator-like small compound, C7, reactivates Epstein-Barr virus (EBV) lytic cycle by activating the ERK1/2-autophagy axis in epithelial cancers. Here, we...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Yiu, Stephanie Pei Tung, Hui, Kwai Fung, Münz, Christian, Lo, Kwok-Wai, Tsao, Sai Wah, Kao, Richard Yi Tsun, Yang, Dan, Chiang, Alan Kwok Shing
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6966612/
https://ncbi.nlm.nih.gov/pubmed/31769432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11121871
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