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High Energy Intake Induced Overexpression of Transcription Factors and Its Regulatory Genes Involved in Acceleration of Hepatic Lipogenesis: A Rat Model for Type 2 Diabetes

Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by impaired insulin action and its secretion. The objectives of the present study were to establish an economical and efficient animal model, mimicking pathophysiology of human T2DM to understand probable molecular mechanisms in c...

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Dettagli Bibliografici
Pubblicato in:Biomedicines
Autori principali: Khadke, Suresh P., Kuvalekar, Aniket A., Harsulkar, Abhay M., Mantri, Nitin
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6966540/
https://ncbi.nlm.nih.gov/pubmed/31569751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines7040076
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