Quantitative Systems Pharmacology for Neuroscience Drug Discovery and Development: Current Status, Opportunities, and Challenges

The substantial progress made in the basic sciences of the brain has yet to be adequately translated to successful clinical therapeutics to treat central nervous system (CNS) diseases. Possible explanations include the lack of quantitative and validated biomarkers, the subjective nature of many clin...

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Vydáno v:CPT Pharmacometrics Syst Pharmacol
Hlavní autoři: Geerts, Hugo, Wikswo, John, van der Graaf, Piet H., Bai, Jane P.F., Gaiteri, Chris, Bennett, David, Swalley, Susanne E., Schuck, Edgar, Kaddurah‐Daouk, Rima, Tsaioun, Katya, Pelleymounter, Mary
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
White Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6966183/
https://ncbi.nlm.nih.gov/pubmed/31674729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12478
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