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Inhibition of SERPINE2/protease nexin-1 by a monoclonal antibody attenuates airway remodeling in a murine model of asthma

SERPINE2, also known as protease nexin-1 (PN-1), is a serine protease inhibitor produced by many cell types and has pleiotropic biological functions. It has been reported that SERPINE2/PN-1 is involved in tissue remodeling of fibrotic diseases including idiopathic pulmonary fibrosis and cardiac fibr...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Pathol
Main Authors: Hu, Chengping, Jiang, Juan, Xun, Qiufen, Zhao, Bingrong, Hu, Xinyue, Deng, Pengbo, Li, Yuanyuan
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6966070/
https://ncbi.nlm.nih.gov/pubmed/31966548
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