Retinoid X receptor ligand regulates RXRα/Nur77-dependent apoptosis via modulating its nuclear export and mitochondrial targeting

Alzheimer’s disease (AD) is the most prevalent neurodegenerative disorder disease in elderly. It is characterized by the formation of amyloid plaques and nerve cells apoptosis in the brain. This study focuses on the association between nerve cells apoptosis and nuclear receptors within AD. Thus, we...

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Vydáno v:Int J Clin Exp Pathol
Hlavní autoři: Wang, Li, Zheng, Yansong, Gao, Xiaoxiao, Liu, Yingchun, You, Xiaoqing
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2017
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6965856/
https://ncbi.nlm.nih.gov/pubmed/31966420
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