Clinical relevance of somatic mutations in main driver genes detected in gastric cancer patients by next-generation DNA sequencing

Somatic mutation profiling in gastric cancer (GC) enables main driver mutations to be identified and their clinical and prognostic value to be evaluated. We investigated 77 tumour samples of GC by next-generation sequencing (NGS) with the Ion AmpliSeq Hotspot Panel v2 and a custom panel covering six...

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Publicado no:Sci Rep
Main Authors: Nemtsova, Marina V., Kalinkin, Alexey I., Kuznetsova, Ekaterina B., Bure, Irina V., Alekseeva, Ekaterina A., Bykov, Igor I., Khorobrykh, Tatiana V., Mikhaylenko, Dmitry S., Tanas, Alexander S., Kutsev, Sergey I., Zaletaev, Dmitry V., Strelnikov, Vladimir V.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6965114/
https://ncbi.nlm.nih.gov/pubmed/31949278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57544-3
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