Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis

Cutaneous malignant melanoma is an aggressive cancer of melanocytes with a strong propensity to metastasize. We posit that melanoma cells acquire metastatic capability by adopting an embryonic-like phenotype, and that a lineage approach would uncover metastatic melanoma biology. Using a genetically...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Marie, Kerrie L., Sassano, Antonella, Yang, Howard H., Michalowski, Aleksandra M., Michael, Helen T., Guo, Theresa, Tsai, Yien Che, Weissman, Allan M., Lee, Maxwell P., Jenkins, Lisa M., Zaidi, M. Raza, Pérez-Guijarro, Eva, Day, Chi-Ping, Ylaya, Kris, Hewitt, Stephen M., Patel, Nimit L., Arnheiter, Heinz, Davis, Sean, Meltzer, Paul S., Merlino, Glenn, Mishra, Pravin J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6965108/
https://ncbi.nlm.nih.gov/pubmed/31949145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-14085-2
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