Protein kinase D1 regulates metabolic switch in pancreatic cancer via modulation of mTORC1

BACKGROUND: Protein kinase D1 (PKD1) is a serine–threonine kinase that regulates various functions within the cell. Herein, we report the significance of PKD1 expression in glucose metabolism resulting in pancreatic cancer (PanCa) progression and chemo-resistance. METHODS: PKD1 expression in PanCa w...

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Bibliografiske detaljer
Udgivet i:Br J Cancer
Main Authors: Kumari, Sonam, Khan, Sheema, Sekhri, Radhika, Mandil, Hassan, Behrman, Stephen, Yallapu, Murali M., Chauhan, Subhash C., Jaggi, Meena
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6964700/
https://ncbi.nlm.nih.gov/pubmed/31819177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-019-0629-9
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