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Microwave-assisted synthesis of 2-substituted 4,5,6,7-tetrahydro-1,3-thiazepines from 4-aminobutanol

A general procedure for the synthesis of 2-substituted tetrahydro-1,3-thiazepines by MW-assisted cyclization of 4-thioamidobutanols is presented. The acyclic precursors were prepared in high overall yields by an expeditious three-step diacylation/thionation/deprotection sequence from 4-aminobutanol....

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Podrobná bibliografie
Vydáno v:Beilstein J Org Chem
Hlavní autoři: Mollo, María C, Kilimciler, Natalia B, Bisceglia, Juan A, Orelli, Liliana R
Médium: Artigo
Jazyk:Inglês
Vydáno: Beilstein-Institut 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6964664/
https://ncbi.nlm.nih.gov/pubmed/31976014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.16.5
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