Co-Prodrugs of 7-Ethyl-10-hydroxycamptothecin and Vorinostat with in Vitro Hydrolysis and Anticancer Effects

[Image: see text] 7-Ethyl-10-hydroxycamptothecin (SN38) and vorinostat (SAHA) are quite promising combination therapy agents applied to the clinical treatment of cancer. In this study, we designed and synthesized a series of novel SN38-SAHA co-prodrugs, which were conjugated by four different amino...

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Detaylı Bibliyografya
Yayımlandı:ACS Omega
Asıl Yazarlar: Liu, Shuangxi, Hu, Zonglong, Zhang, Qiumeng, Zhu, Qiwen, Chen, Yi, Lu, Wei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2019
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6964270/
https://ncbi.nlm.nih.gov/pubmed/31956782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b02786
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