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The effects of the DNA Demethylating reagent, 5-azacytidine on SMCHD1 genomic localization

BACKGROUND: DNA methylation is an epigenetic modification that mainly repress expression of genes essential during embryogenesis and development. There are key ATPase-dependent enzymes that read or write DNA methylation to remodel chromatin and regulate gene expression. Structural maintenance of chr...

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Detalhes bibliográficos
Publicado no:BMC Genet
Main Authors: Massah, S., Jubene, J., Lee, F. J. S., Beischlag, T. V., Prefontaine, G. G.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6964063/
https://ncbi.nlm.nih.gov/pubmed/31941450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-020-0809-x
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